Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CTSB | P07858 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | GRN | P28799 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6927032 | 0.85 | CCR1 (0.49) | CTSKCTSBCTSLCTSSCCR1 | |
| SCHEMBL6925973 | 0.82 | TAS1R3 (0.56) | CTSKCTSBCTSLCTSSHDAC1 | |
| SCHEMBL7464557 | 0.80 | GRN (0.52) | CTSKCTSBCTSLCTSSCCR1 | |
| SCHEMBL6927425 | 0.79 | CTSL (0.55) | CTSKCTSBCTSLCTSSCNR2 | |
| SCHEMBL6620714 | 0.78 | CTSK (0.60) | CTSKCTSBCTSLCTSS | |
| SCHEMBL7463889 | 0.78 | CTSL (0.49) | CTSKCTSBCTSLCTSSCNR2 | |
| SCHEMBL7463004 | 0.77 | CTSK (0.49) | CTSKCTSBCTSLCTSSHDAC1 | |
| SCHEMBL7462272 | 0.77 | CTSL (0.50) | CTSKCTSBCTSLCTSSCCR1 | |
| SCHEMBL7467134 | 0.76 | CTSK (0.43) | CTSKCTSBCTSLCTSSCNR2 | |
| SCHEMBL7462346 | 0.75 | CTSK (0.47) | CTSKCTSBCTSLCTSSCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | claimed |
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | disclosed |