Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 5/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925973 | 0.90 | TAS1R3 (0.56) | CCR1CTSBCTSKTAS1R3TAS1R1 | |
| SCHEMBL6926811 | 0.85 | CTSK (0.48) | CCR1CTSBCTSKGRNSORT1 | |
| SCHEMBL7473345 | 0.83 | TAS1R3 (0.54) | CCR1CTSBCTSKTAS1R3TAS1R1 | |
| SCHEMBL6927425 | 0.83 | CTSL (0.55) | CTSBCTSKCTSLCTSS | |
| SCHEMBL7462272 | 0.80 | CTSL (0.50) | CCR1CTSBCTSKTAS1R3TAS1R1 | |
| SCHEMBL7464557 | 0.79 | GRN (0.52) | CCR1CTSBCTSKGRNSORT1 | |
| SCHEMBL6620714 | 0.77 | CTSK (0.60) | CTSBCTSKCTSLCTSS | |
| SCHEMBL7467134 | 0.76 | CTSK (0.43) | CTSBCTSKTAS1R3TAS1R1CTSL | |
| SCHEMBL7467318 | 0.76 | CTSL (0.53) | CTSBCTSKCTSLCTSS | |
| SCHEMBL7462366 | 0.76 | CTSS (0.53) | CTSBCTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | claimed |
| US-6518267-B1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-02-11 | — | — | US | disclosed |