Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929721 | 0.85 | ACHE (0.43) | ACHETLR7LMNATSHRHTT | |
| SCHEMBL6926916 | 0.82 | CSF1R (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL6923561 | 0.79 | HTR4 (0.41) | ACHEHTR1AHTR4TLR7LMNA | |
| SCHEMBL6702926 | 0.75 | TLR7 (0.44) | HTR2AHTR2BTLR7LMNAHTT | |
| SCHEMBL6929033 | 0.72 | KMT2A (0.46) | ACHESMN1; SMN2HTR1AHTR2ADRD2 | |
| SCHEMBL6701754 | 0.70 | LMNA (0.39) | SMN1; SMN2HTR2AHTR2BTLR7LMNA | |
| SCHEMBL6925393 | 0.70 | ACHE (0.46) | ACP1ACHEHTR2AHTR2BTLR7 | |
| SCHEMBL6929452 | 0.69 | TLR7 (0.54) | ACHEHTR2AHTR2BTLR7LMNA | |
| SCHEMBL27552337 | 0.69 | ACHE (0.48) | ACHEHTR2AHTR2BTLR7LMNA | |
| SCHEMBL7096192 | 0.69 | LMNA (0.40) | HTR2AHTR2BTLR7LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |