Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 4/20 | 0.42 |
| ▸ | KCNK13 | Q9HB14 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | ACP1 | P24666 | 5/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | HTR6 | P50406 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929821 | 0.90 | HTR4 (0.40) | NPY1RKCNK13HTR4ACP1JAK2 | |
| SCHEMBL6840099 | 0.87 | NPY1R (0.37) | NPY1RKCNK13HTR4ACP1JAK2 | |
| SCHEMBL6925914 | 0.85 | NPY1R (0.44) | NPY1RHTR4ACP1MAOBHTR6 | |
| SCHEMBL6927725 | 0.85 | NPY1R (0.41) | NPY1RHTR4ACP1MAOBHTR6 | |
| Hydrochloric Acid SCHEMBL6923145 | 0.84 | NPY1R (0.43) | NPY1RHTR4ACP1MAOBHTR6 | |
| SCHEMBL6927043 | 0.83 | NPY1R (0.41) | NPY1RHTR4ACP1MAOBHTR6 | |
| SCHEMBL6922923 | 0.82 | NPY1R (0.41) | NPY1RHTR4ACP1MAOBHTR6 | |
| SCHEMBL6929551 | 0.81 | PDE6D (0.41) | NPY1RHTR4ACP1MAOBHTR6 | |
| SCHEMBL6928340 | 0.80 | ALDH1A1 (0.42) | NPY1RHTR4MAOBHTR6 | |
| SCHEMBL6927683 | 0.80 | NPY1R (0.40) | NPY1RHTR4ACP1MAOBHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518265-B1 | 1H-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1104764-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2001-06-06 | — | — | EP | disclosed |