Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.41 |
| ▸ | SELE | P16581 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924085 | 0.87 | ERN1 (0.43) | TDP1ICAM1SELEALDH1A1MEN1 | |
| SCHEMBL6926229 | 0.78 | ALDH1A1 (0.50) | TDP1ICAM1SELEALDH1A1MEN1 | |
| SCHEMBL6928332 | 0.77 | MLYCD (0.43) | ICAM1SELEALDH1A1MEN1KMT2A | |
| SCHEMBL6765841 | 0.76 | L3MBTL1 (0.48) | TDP1ICAM1SELEALDH1A1MEN1 | |
| SCHEMBL4866236 | 0.75 | TDP1 (0.55) | TDP1ALDH1A1MEN1KMT2AERN1 | |
| SCHEMBL20535763 | 0.75 | MEN1 (0.61) | TDP1ALDH1A1MEN1KMT2AERN1 | |
| SCHEMBL16666323 | 0.73 | TDP1 (0.52) | TDP1ALDH1A1MEN1KMT2AERN1 | |
| SCHEMBL2271692 | 0.73 | HDAC1 (0.57) | TDP1ICAM1ALDH1A1MEN1KMT2A | |
| SCHEMBL31345532 | 0.72 | ALDH1A1 (0.56) | TDP1ALDH1A1MEN1KMT2AHTR1A | |
| SCHEMBL25078348 | 0.72 | TDP1 (0.55) | TDP1ICAM1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |