Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763816 | 0.88 | ERN1 (0.49) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL27577770 | 0.83 | ALDH1A1 (0.45) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL8736422 | 0.79 | ACHE (0.48) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL6927202 | 0.78 | TDP1 (0.46) | ALDH1A1ERN1MAPTGAATDP1 | |
| SCHEMBL8738414 | 0.78 | MAPT (0.58) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL31345518 | 0.78 | MAPT (0.58) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL7756787 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL5320711 | 0.76 | ALDH1A1 (0.54) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| Nitrogen SCHEMBL10783880 | 0.75 | MAPT (0.55) | ALDH1A1MAPTHPGDKDM4EHTT | |
| SCHEMBL6928332 | 0.75 | MLYCD (0.43) | ALDH1A1MAPTHPGDHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |