Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6435421 | 0.80 | CXCR4 (0.47) | MAOAMAOBDRD2CXCR4 | |
| SCHEMBL6925802 | 0.80 | CXCR4 (0.47) | MAOAMAOBDRD2CXCR4 | |
| SCHEMBL6929788 | 0.80 | CXCR4 (0.47) | MAOAMAOBDRD2CXCR4 | |
| SCHEMBL6928850 | 0.80 | CXCR4 (0.40) | MAOAMAOBCXCR4 | |
| SCHEMBL6930890 | 0.78 | CXCR4 (0.47) | MAOAMAOBDRD2CXCR4 | |
| SCHEMBL6928172 | 0.78 | MAOA (0.49) | MAOAMAOBEPHX2ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL6930816 | 0.77 | MAOA (0.48) | MAOAMAOBEPHX2ALDH1A1HTT | |
| SCHEMBL8843210 | 0.73 | CXCR4 (0.55) | DRD2CXCR4 | |
| SCHEMBL7596716 | 0.71 | TRPM8 (0.51) | EPHX2TRPM8 | |
| SCHEMBL9018937 | 0.70 | DRD2 (0.65) | DRD3MAOAMAOBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646188-A | FOR TREATING NEUROTRAUMA | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1997-07-08 | — | — | US | claimed |
| EP-0865276-A4 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | GILAD GAD (IL) | 2003-07-30 | — | — | EP | disclosed |
| EP-0865276-A1 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | Gilad, Gad (IL) | 1998-09-23 | — | — | EP | disclosed |
| US-5646188-A | FOR TREATING NEUROTRAUMA | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1997-07-08 | — | — | US | disclosed |
| WO-1997002027-A1 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1997-01-23 | — | — | WO | disclosed |