Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930890 | 0.89 | CXCR4 (0.47) | CXCR4MAOAMAOB | |
| SCHEMBL6929788 | 0.87 | CXCR4 (0.47) | CXCR4MAOAMAOB | |
| SCHEMBL6435421 | 0.87 | CXCR4 (0.47) | CXCR4MAOAMAOB | |
| SCHEMBL6925802 | 0.87 | CXCR4 (0.47) | CXCR4MAOAMAOB | |
| SCHEMBL8843210 | 0.81 | CXCR4 (0.55) | CXCR4 | |
| SCHEMBL6928124 | 0.80 | DRD3 (0.39) | CXCR4MAOAMAOB | |
| SCHEMBL9018937 | 0.72 | DRD2 (0.65) | MAOAMAOB | |
| SCHEMBL5679810 | 0.72 | ALDH1A1 (0.46) | CXCR4 | |
| SCHEMBL6926306 | 0.70 | MAOA (0.56) | MAOAMAOB | |
| SCHEMBL29269190 | 0.68 | DRD2 (0.51) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865276-A4 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | GILAD GAD (IL) | 2003-07-30 | — | — | EP | claimed |
| EP-0865276-A1 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | Gilad, Gad (IL) | 1998-09-23 | — | — | EP | claimed |
| US-5646188-A | FOR TREATING NEUROTRAUMA | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1997-07-08 | — | — | US | claimed |
| WO-1997002027-A1 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1997-01-23 | — | — | WO | claimed |
| EP-0865276-A4 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | GILAD GAD (IL) | 2003-07-30 | — | — | EP | disclosed |
| EP-0865276-A1 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | Gilad, Gad (IL) | 1998-09-23 | — | — | EP | disclosed |
| US-5646188-A | FOR TREATING NEUROTRAUMA | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1997-07-08 | — | — | US | disclosed |
| WO-1997002027-A1 | POLYAMINE DERIVATIVES OF 1-AMINOINDAN | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1997-01-23 | — | — | WO | disclosed |