Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237597 | 0.83 | CHRM2 (0.47) | TAAR1CHRM3ADRA2AADRA2BADRA2C | |
| SCHEMBL4315585 | 0.83 | TAAR1 (0.50) | TAAR1CHRM3MAOBHPGDADRA2A | |
| SCHEMBL8596525 | 0.82 | TAAR1 (0.64) | TAAR1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL10593611 | 0.82 | TAAR1 (0.42) | TAAR1CHRM3MAOBADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8097795 | 0.81 | TAAR1 (0.62) | TAAR1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL2495001 | 0.80 | TAAR1 (0.40) | TAAR1MAOBHPGDSMN1; SMN2 | |
| SCHEMBL2337879 | 0.80 | CHRM3 (0.47) | TAAR1CHRM3MAOBHPGDADRA2A | |
| SCHEMBL10792626 | 0.78 | TSHR (0.44) | TAAR1CHRM3MAOBHPGDADRA2A | |
| SCHEMBL21518167 | 0.78 | TAAR1 (0.38) | TAAR1KDM4E | |
| SCHEMBL19675835 | 0.78 | TAAR1 (0.39) | TAAR1HPGDSMN1; SMN2KDM4EIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109863160-B | Nucleoside phosphate compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2022-06-07 | — | — | CN | disclosed |
| US-10899786-B2 | Nucleoside phosphate compound and preparation method and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-01-26 | — | — | US | disclosed |
| US-20200308214-A1 | NUCLEOSIDE PHOSPHATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2020-10-01 | — | — | US | disclosed |
| EP-3560943-A1 | NUCLEOSIDE PHOSPHATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2019-10-30 | — | — | EP | disclosed |
| CN-109863160-A | Nucleoside phosphorylase class compound and its preparation method and application | 四川科伦博泰生物医药股份有限公司 | 2019-06-07 | — | — | CN | disclosed |
| US-6518450-B2 | Adrenergic blocking agent | NATIONAL SCIENCE COUNCIL (TW) | 2003-02-11 | — | — | US | disclosed |
| US-20010056211-A1 | Guaiacoxypropanolamines with alpha/beta adrenergic blocking activity | NATIONAL SCIENCE COUNCIL (TW) | 2001-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200308214-A1 | NUCLEOSIDE PHOSPHATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | PNP, NTPCR, TYMP | TAAR1 4584/4885CHRM3 4866/4885MAOB 1491/4885 |
| US-10899786-B2 | Nucleoside phosphate compound and preparation method and use thereof | PNP, NTPCR, TYMP | TAAR1 4584/4885CHRM3 4866/4885MAOB 1491/4885 |
| US-20010056211-A1 | Guaiacoxypropanolamines with alpha/beta adrenergic blocking activity | ADRB1, ADRA1A, ADRA1B | TAAR1 204/4885CHRM3 140/4885MAOB 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.