Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079544 | 0.89 | CHRM3 (0.45) | CHRM3MAOBTAAR1ADRA2AADRA2B | |
| Ethylene Glycol SCHEMBL7751137 | 0.88 | MAOB (0.46) | CHRM3MAOBTAAR1ADRA2AADRA2B | |
| SCHEMBL4846056 | 0.87 | CHRM3 (0.44) | CHRM3MAOBTAAR1ADRA2AADRA2B | |
| SCHEMBL4669318 | 0.85 | FFAR1 (0.45) | CHRM3MAOBALDH1A1RECQLGBA1 | |
| SCHEMBL23343755 | 0.83 | MAOB (0.46) | CHRM3MAOBTAAR1ADRA2AADRA2B | |
| SCHEMBL4315585 | 0.83 | TAAR1 (0.50) | CHRM3MAOBTAAR1ADRA2AADRA2B | |
| SCHEMBL10593611 | 0.82 | TAAR1 (0.42) | CHRM3MAOBTAAR1ADRA2AADRA2B | |
| O-Xylene SCHEMBL27533464 | 0.81 | TSHR (0.50) | ALDH1A1RECQLHTR1AKDM4ETHRB | |
| SCHEMBL2491945 | 0.80 | FFAR1 (0.36) | CHRM3ALDH1A1GBA1KDM4E | |
| SCHEMBL6928728 | 0.80 | TAAR1 (0.55) | CHRM3MAOBTAAR1ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776359-B1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2011-08-24 | — | — | EP | disclosed |
| US-20080076766-A1 | Piperidine Derivatives As Renin Inhibitor | SPEEDEL EXPERIMENTA AG (CH) | 2008-03-27 | — | — | US | disclosed |
| EP-1816122-A2 | 3,4,5-substituted piperidines as therapeutic compounds | Speedel Experimenta AG (CH) | 2007-08-08 | — | — | EP | disclosed |
| CN-101014594-A | Piperidine derivatives as renin inhibitors | SPEEDEL EXPERIMENTA AG (CH) | 2007-08-08 | — | — | CN | disclosed |
| US-20070167433-A1 | 3,4,5-Substituted piperidines as therapeutic compounds | SPEEDEL EXPERIMENTA AG (CH) | 2007-07-19 | — | — | US | disclosed |
| EP-1776359-A2 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | Speedel Experimenta AG (CH) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006005741-A2 | PIPERDINE DERIVATIVES AS RENIN INHIBITORS | SPEEDEL EXPERIMENTA AG (CH) | 2006-01-19 | — | — | WO | disclosed |
| US-4584396-A | Substituted phenoxypropionates and herbicidal compositions | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-04-22 | — | — | US | disclosed |
| EP-0068260-B1 | SUBSTITUTED PHENOXYPROPIONATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-03-05 | — | — | EP | disclosed |
| EP-0086392-B1 | HERBICIDAL AGENT CONTAINING METAMITRON IN COMBINATION WITH CERTAIN PHENOXYPROPIONIC-ACID ESTERS | BAYER AG (DE) | 1985-08-21 | — | — | EP | disclosed |
| US-4441913-A | PRE- AND POST-EMERGENCE | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-10 | — | — | US | disclosed |
| EP-0086392-A1 | Herbicidal agent containing metamitron in combination with certain phenoxypropionic-acid esters | BAYER AG (DE) | 1983-08-24 | — | — | EP | disclosed |
| EP-0084819-A2 | Herbicidal agents containing methabenzthiazuron in combination with certain phenoxypropionic acid esters | BAYER AG (DE) | 1983-08-03 | — | — | EP | disclosed |
| EP-0068260-A2 | Substituted phenoxypropionates, process for their preparation and their use as herbicides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076766-A1 | Piperidine Derivatives As Renin Inhibitor | REN, AGTR1, ACE | CHRM3 367/4885MAOB 526/4885TAAR1 654/4885 |
| US-20070167433-A1 | 3,4,5-Substituted piperidines as therapeutic compounds | CTSD, CTSL, CTSZ | CHRM3 1960/4885MAOB 2859/4885TAAR1 4652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.