SCHEMBL6928802

SCHEMBL6928802

CCO[PH](=O)OCC.O=c1[c]cc2cc(S(=O)(=O)Cl)c(C(F)(F)F)cc2[nH]1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6923608 0.89 CA1 (0.36)
SCHEMBL6934908 0.86 TRPV4 (0.38) TRPV4
SCHEMBL6928525 0.82 AR (0.35)
SCHEMBL6935418 0.74 CA2 (0.46)
Phosphonic Acid SCHEMBL7070319 0.74 CA1 (0.41)
SCHEMBL6938290 0.73 CNR2 (0.36)
SCHEMBL6935736 0.73 CNR2 (0.37)
SCHEMBL6937670 0.73 KIF11 (0.35)
SCHEMBL6935366 0.70
SCHEMBL6928804 0.69 TRPV4 (0.31) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6518258-B1 6-sulphamoyl -3-quinolyphosphonic acid compounds LES LABORATOIRES SERVIER (FR) 2003-02-11 US disclosed