SCHEMBL6937670

SCHEMBL6937670

CNS(=O)(=O)c1cc2c[c]c(=O)[nH]c2cc1C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.35
TAS2R14 Q9NYV8 1/20 0.32
AR P10275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6938290 0.84 CNR2 (0.36) AR
SCHEMBL6935418 0.82 CA2 (0.46) KIF11AR
SCHEMBL6934908 0.82 TRPV4 (0.38)
SCHEMBL6940841 0.80 KMT2A (0.35) TAS2R14
Phosphonic Acid SCHEMBL7070319 0.77 CA1 (0.41)
SCHEMBL6935736 0.77 CNR2 (0.37) AR
SCHEMBL6937263 0.76 TSHR (0.42)
SCHEMBL7652393 0.74 TAS2R14 (0.34) KIF11TAS2R14
SCHEMBL6928802 0.73 TRPV4 (0.30)
SCHEMBL6923608 0.73 CA1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1125942-B1 Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-04-09 EP disclosed
EP-1125942-A1 Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 2001-08-22 EP disclosed