Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937670 | 0.84 | KIF11 (0.35) | AR | |
| SCHEMBL6934342 | 0.82 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1LMNACA12CA9 | |
| SCHEMBL6935736 | 0.79 | CNR2 (0.37) | CNR2CNR1ARALDH1A1KDM4E | |
| SCHEMBL6935418 | 0.77 | CA2 (0.46) | CNR2ARALDH1A1LMNACA12 | |
| SCHEMBL6934908 | 0.77 | TRPV4 (0.38) | CA12CA9 | |
| SCHEMBL7647528 | 0.77 | KDM4E (0.34) | CNR2CNR1ARALDH1A1CA12 | |
| SCHEMBL6942103 | 0.75 | ALDH1A1 (0.40) | CNR2CNR1ALDH1A1CA12CA9 | |
| SCHEMBL7648880 | 0.75 | CNR2 (0.32) | CNR2CNR1ARL3MBTL1ALDH1A1 | |
| SCHEMBL7647530 | 0.74 | CNR2 (0.33) | CNR2CNR1ARCA12CA9 | |
| SCHEMBL6928802 | 0.73 | TRPV4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |