Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.65 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.65 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.63 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.63 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.63 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.63 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.63 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.63 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.63 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.63 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.63 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.63 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.63 |
| ▸ | PSMB6 | P28072 | 3/20 | 0.63 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.63 |
| ▸ | PSMB10 | P40306 | 3/20 | 0.63 |
| ▸ | PSMB3 | P49720 | 3/20 | 0.63 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.63 |
| ▸ | PSMA6 | P60900 | 3/20 | 0.63 |
| ▸ | PSMA8 | Q8TAA3 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929184 | 1.00 | SOAT2 (0.65) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL6929182 | 1.00 | SOAT2 (0.65) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL6925332 | 0.93 | ALDH1A1 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL6931888 | 0.93 | ALDH1A1 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL6927751 | 0.93 | ALDH1A1 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL6924375 | 0.93 | ALDH1A1 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL6927754 | 0.93 | ALDH1A1 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL6925330 | 0.93 | ALDH1A1 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL6924373 | 0.93 | ALDH1A1 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 | |
| SCHEMBL6931891 | 0.93 | ALDH1A1 (0.54) | SOAT2SOAT1PSMB11PSMA7PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624196-B2 | Particularly gelatinase A, collagenase-3, and stromelysin-1 and for the treatment of multiple sclerosis, cardiovascular disorders | WARNER-LAMBERT COMPANY | 2003-09-23 | — | — | US | claimed |
| US-6541521-B1 | Particularly gelatinase A, collagenase-3, and stromelysin-1 | WARNER-LAMBERT COMPANY | 2003-04-01 | — | — | US | claimed |
| US-20020161050-A1 | Benzene butyric acids and their derivatives as inhibitors of matrix metalloproteinases | WARNER-LAMBERT COMPANY (US) | 2002-10-31 | — | — | US | claimed |
| US-6624196-B2 | Particularly gelatinase A, collagenase-3, and stromelysin-1 and for the treatment of multiple sclerosis, cardiovascular disorders | WARNER-LAMBERT COMPANY | 2003-09-23 | — | — | US | disclosed |
| US-6541521-B1 | Particularly gelatinase A, collagenase-3, and stromelysin-1 | WARNER-LAMBERT COMPANY | 2003-04-01 | — | — | US | disclosed |
| US-20020161050-A1 | Benzene butyric acids and their derivatives as inhibitors of matrix metalloproteinases | WARNER-LAMBERT COMPANY (US) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161050-A1 | Benzene butyric acids and their derivatives as inhibitors of matrix metalloproteinases | MMP1, MMP8, MMP13 | SOAT2 4322/4885SOAT1 4007/4885PSMB11 117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.