Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065100 | 0.81 | TRPV4 (0.37) | TRPV4KDM4EMAPK1MAPTS1PR4 | |
| SCHEMBL4061746 | 0.75 | TRPV4 (0.33) | TRPV4KMT2AMEN1 | |
| SCHEMBL7026006 | 0.74 | MAPT (0.44) | KDM4EMAPTKMT2ALMNAMEN1 | |
| SCHEMBL6432730 | 0.73 | — | — | |
| SCHEMBL11502295 | 0.72 | CHEK1 (0.38) | KDM4ENPSR1ALDH1A1GAATSHR | |
| SCHEMBL10730132 | 0.70 | — | — | |
| SCHEMBL7034477 | 0.70 | MAPT (0.47) | KDM4EMAPTHSP90AA1RAB9ALMNA | |
| SCHEMBL7029160 | 0.70 | PRKCI (0.38) | MAPK1MAPTRAB9AALDH1A1LMNA | |
| SCHEMBL7031921 | 0.68 | POLB (0.41) | KDM4EMAPTALDH1A1TSHRKMT2A | |
| SCHEMBL1500874 | 0.67 | CA2 (0.46) | TRPV4KDM4EMAPK1MAPTS1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1221552-C | N- ((1,2, 4) triazoloazinyl) thiophene sulfonamide compounds as herbicides | DOW AGROSCIENCES LLC (US) | 2005-10-05 | — | — | CN | disclosed |
| CN-1471533-A | N-([1,2,4] triazoloazinyl) thiophene sulfonamide compounds as herbicides | �ݶ�ũ������˾ | 2004-01-28 | — | — | CN | disclosed |
| US-6645918-B1 | N-(Triazolo(1,5-a)pyrimidinyl)thiophenesulfonamide compounds; postemergence herbicides; agriculture | DOW AGROSCIENCES LLC | 2003-11-11 | — | — | US | disclosed |
| US-20030199393-A1 | N- ([1,2,4,] TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | ARNDT KIM ERIC (US) | 2003-10-23 | — | — | US | disclosed |
| EP-1330458-A1 | N-( 1,2,4]TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AS HERBICIDES | Dow Agrosciences LLC (US) | 2003-07-30 | — | — | EP | disclosed |
| US-6518222-B2 | Prepared from 2-amino(1,2,4)triazolo(1,5-c)pyrimidine, 2-amino(1,2,4)triazolo(1,5-a)pyrimidine, and 2-amino(1,2,4)triazolo(1,5-a)pyridine compounds and thiophenesulfonyl chloride compounds | DOW AGROSCIENCES LLC | 2003-02-11 | — | — | US | disclosed |
| US-20020094935-A1 | N-([1,2,4] triazoloazinyl) thiophenesulfonamide compounds and their use as herbicides | DOW AGROSCIENCES LLC | 2002-07-18 | — | — | US | disclosed |
| WO-2002038572-A1 | N-([1,2,4]TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2002-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094935-A1 | N-([1,2,4] triazoloazinyl) thiophenesulfonamide compounds and their use as herbicides | PNPO, NAT1, DDT | TRPV4 3109/4885KDM4E 1222/4885MAPK1 2411/4885 |
| US-20030199393-A1 | N- ([1,2,4,] TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | NAT1, TST, TASP1 | TRPV4 1818/4885KDM4E 1937/4885MAPK1 2349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.