Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | CES2 | O00748 | 3/20 | 0.69 |
| ▸ | CES1 | P23141 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9282441 | 0.93 | LMNA (0.69) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL3757038 | 0.91 | CES2 (0.55) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL27583890 | 0.86 | LMNA (0.69) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL4293775 | 0.84 | L3MBTL1 (0.69) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL37126 | 0.84 | LMNA (0.78) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL10487734 | 0.83 | LMNA (0.60) | LMNACES2CES1ALDH1A1KDM4E | |
| SCHEMBL30306610 | 0.83 | ALDH1A1 (0.52) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL29167409 | 0.83 | LMNA (0.91) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL10646810 | 0.83 | LMNA (0.91) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL27562303 | 0.83 | LMNA (0.91) | LMNACES2CES1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1216142-A4 | THERMOFORMABLE OPHTHALMIC LENS | NOVARTIS AG (CH) | 2003-06-11 | — | — | EP | disclosed |
| EP-1216142-A1 | THERMOFORMABLE OPHTHALMIC LENS | Wesley Jessen Corporation (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2001005578-A1 | THERMOFORMABLE OPHTHALMIC LENS | WESLEY-JESSEN CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |
| US-5466721-A | Citral acetal ethers of alpha-hydroxy phenyl ketones and radiation curable compositions thereof | HENKEL CORPORATION (US) | 1995-11-14 | — | — | US | disclosed |
| WO-1994029355-A1 | CITRAL ACETAL ETHERS OF ALPHA-HYDROXY PHENYL KETONES AND POLYMERIZABLE COMPOSITIONS | HENKEL CORPORATION (US) | 1994-12-22 | — | — | WO | disclosed |