Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 7/20 | 0.55 |
| ▸ | CES1 | P23141 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930896 | 0.91 | LMNA (0.69) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL9282441 | 0.91 | LMNA (0.69) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL30306610 | 0.81 | ALDH1A1 (0.52) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL23419503 | 0.81 | ALDH1A1 (0.50) | CES2CES1LMNAALDH1A1TSHR | |
| SCHEMBL12412504 | 0.79 | ABCG2 (0.44) | CES2CES1LMNAALDH1A1TAS1R3 | |
| SCHEMBL11455668 | 0.78 | KDM4E (0.59) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL9252175 | 0.78 | TAS1R3 (0.51) | LMNAALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL8149482 | 0.77 | CES2 (0.60) | CES2CES1LMNAALDH1A1KDM4E | |
| SCHEMBL30306602 | 0.76 | ALDH1A1 (0.44) | LMNAALDH1A1TSHRTDP1TAS1R3 | |
| SCHEMBL27583890 | 0.76 | LMNA (0.69) | CES2CES1LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8597579-B1 | Molecularly imprinted polymer-denuder based sensors | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2013-12-03 | — | — | US | claimed |
| US-20120164027-A1 | Polymer Based Lanthanide Luminescent Sensors for the Detection of Organophosphorus Compounds | MURRAY GEORGE M (US) | 2012-06-28 | — | — | US | claimed |
| US-7416703-B2 | Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds | THE JOHNS HOPKINS UNIVERSITY (US) | 2008-08-26 | — | — | US | claimed |
| US-20050019218-A1 | Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds | MURRAY GEORGE M (US) | 2005-01-27 | — | — | US | claimed |
| US-20040265178-A1 | Molecularly imprinted polymer solution anion sensor | MURRAY GEORGE M (US) | 2004-12-30 | — | — | US | claimed |
| EP-1436599-A2 | MOLECULARLY IMPRINTED POLYMER SOLUTION ANION SENSOR | The Johns Hopkins University (US) | 2004-07-14 | — | — | EP | claimed |
| US-6749811-B2 | QUANTITATIVE ANALYSIS; USING POLYMER BOUND TO RARE EARTH COMPOUND; WATER POLLUTION CONTROL | THE JOHNS HOPKINS UNIVERSITY | 2004-06-15 | — | — | US | claimed |
| US-20030129092-A1 | Molecularly imprinted polymer solution anion sensor | JOHN HOPKINS UNIVERSITY, THE | 2003-07-10 | — | — | US | claimed |
| WO-2003034043-A2 | MOLECULARLY IMPRINTED POLYMER SOLUTION ANION SENSOR | THE JOHNS HOPKINS UNIVERSTIY (US) | 2003-04-24 | — | — | WO | claimed |
| US-8597579-B1 | Molecularly imprinted polymer-denuder based sensors | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2013-12-03 | — | — | US | disclosed |
| US-20120164027-A1 | Polymer Based Lanthanide Luminescent Sensors for the Detection of Organophosphorus Compounds | MURRAY GEORGE M (US) | 2012-06-28 | — | — | US | disclosed |
| US-7842830-B2 | Transition-metal charge-transport materials, methods of fabrication thereof, and methods of use thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-11-30 | — | — | US | disclosed |
| US-7416703-B2 | Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds | THE JOHNS HOPKINS UNIVERSITY (US) | 2008-08-26 | — | — | US | disclosed |
| US-20080121870-A1 | Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof | GEORGIA TECH RESEACH CORPORATION | 2008-05-29 | — | — | US | disclosed |
| WO-2003033575-A1 | POLYMER BASED PERMEABLE MEMBRANE FOR REMOVAL OF IONS | THE JOHNS HOPKINS UNIVERSITY (US) | 2003-04-24 | — | — | WO | disclosed |
| WO-2003034043-A2 | MOLECULARLY IMPRINTED POLYMER SOLUTION ANION SENSOR | THE JOHNS HOPKINS UNIVERSTIY (US) | 2003-04-24 | — | — | WO | disclosed |
| US-20030003587-A1 | Molecularly imprinted polymer based sensors for the detection of narcotics | JOHNS HOPKINS UNIVERSITY, THE | 2003-01-02 | — | — | US | disclosed |
| WO-2001077672-A2 | MOLECULARLY IMPRINTED POLYMER BASED SENSORS FOR THE DETECTION OF NARCOTICS | THE JOHNS HOPKINS UNIVERSITY (US) | 2001-10-18 | — | — | WO | disclosed |
| US-4187361-A | CONTAINING BENZOIN OXIME GROUPS | GENERAL ELECTRIC COMPANY (US) | 1980-02-05 | — | — | US | disclosed |
| US-4110312-A | OXIDATIVE COUPLING OF A PHENOL, MANGANESE COMPLEX CATALYST | GENERAL ELECTRIC COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080121870-A1 | Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof | SLC39A3, SLC6A6, SLC6A9 | CES2 1387/4885CES1 4295/4885LMNA 1038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.