Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 9/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27679768 | 0.81 | CA2 (0.44) | CA2CA5AALDH1A1MAPTPOLB | |
| SCHEMBL13247952 | 0.81 | ALDH1A1 (0.43) | CA2CA5AALDH1A1MAPTPOLB | |
| SCHEMBL5028741 | 0.76 | NR1H2 (0.42) | CA5AESR1ESR2CYP19A1HSD17B1 | |
| SCHEMBL693345 | 0.76 | ALDH1A1 (0.56) | CA2CA5AALDH1A1MAPTPOLB | |
| SCHEMBL944163 | 0.76 | ALDH1A1 (0.50) | CA2CA5AESR1ESR2ALDH1A1 | |
| SCHEMBL5634830 | 0.76 | ALOX15 (0.45) | CA2CA5AALDH1A1MAPTPOLB | |
| SCHEMBL2705285 | 0.76 | TSHR (0.45) | CA2CA5AESR1ESR2ALDH1A1 | |
| SCHEMBL8528307 | 0.76 | CYP19A1 (0.42) | ESR1ESR2ARCYP19A1HSD17B1 | |
| SCHEMBL3848854 | 0.72 | MCL1 (0.52) | CA5AESR1ESR2MAPTHSD17B1 | |
| SCHEMBL6828399 | 0.72 | MAOB (0.42) | CA2CA5AALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199560-A1 | Bisaryl compound and medicament for cancer treatment comprising the same | KYOWA HAKKO KOGYO CO., LTD. | 2003-10-23 | — | — | US | disclosed |
| US-6608061-B2 | Antiproliferative agents | KYOMA HAKKO KOGYO CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| US-20030018070-A1 | BISARYL COMPOUND AND MEDICAMENT FOR CANCER TREATMENT COMPRISING THE SAME | FUJIFILM CORPORATION (JP) | 2003-01-23 | — | — | US | disclosed |
| EP-0990439-A1 | BISARYL COMPOUNDS AND CANCER REMEDIES CONTAINING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018070-A1 | BISARYL COMPOUND AND MEDICAMENT FOR CANCER TREATMENT COMPRISING THE SAME | AR, NR5A1, SRD5A1 | CA2 1779/4885CA5A 628/4885ESR1 1006/4885 |
| US-20030199560-A1 | Bisaryl compound and medicament for cancer treatment comprising the same | AR, NR5A1, SRD5A1 | CA2 1779/4885CA5A 628/4885ESR1 1006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.