SCHEMBL8528307

SCHEMBL8528307

N#CCSc1ccc(O)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.42
AR P10275 1/20 0.36
ESR1 P03372 11/20 0.35
ESR2 Q92731 11/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
DAO P14920 1/20 0.33
SHBG P04278 1/20 0.33
P4HB P07237 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8746024 0.79 CYP19A1 (0.32) CYP19A1MAOAMAOB
SCHEMBL8526638 0.79 CYP19A1 (0.44) CYP19A1ARESR1ESR2MAOA
SCHEMBL8529340 0.79 ALOX15 (0.41) CYP19A1MAOAMAOB
SCHEMBL9360204 0.76 TSHR (0.36) MAOAMAOB
SCHEMBL6930947 0.76 CA2 (0.40) CYP19A1ARESR1ESR2P4HB
SCHEMBL20384352 0.75 IDO1 (0.43) MAOAMAOBDAO
SCHEMBL23340738 0.75 RXFP1 (0.46) MAOAMAOB
SCHEMBL1060696 0.74 CA2 (0.44) CYP19A1ESR1ESR2SHBGHSD17B1
SCHEMBL24735516 0.73 SHBG (0.34) CYP19A1ESR1ESR2SHBGHSD17B1
SCHEMBL7952409 0.72 MAOA (0.52) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0692033-B1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECH GROUP (GB) 1998-03-11 EP claimed
EP-0505198-B1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL IND LTD (JP) 1997-01-02 EP claimed
US-5512451-A MIXTURE OF A AROMATIC DIACYL CYCLIC HYDRAZIDE, PEROXIDASE CATALYST AND OXIDIZER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US claimed
EP-0692033-A1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BTG INTERNATIONAL LIMITED (GB) 1996-01-17 EP claimed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO claimed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP claimed
EP-0692033-B1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECH GROUP (GB) 1998-03-11 EP disclosed
EP-0505198-B1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL IND LTD (JP) 1997-01-02 EP disclosed
US-5512451-A MIXTURE OF A AROMATIC DIACYL CYCLIC HYDRAZIDE, PEROXIDASE CATALYST AND OXIDIZER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1996-04-30 US disclosed
EP-0692033-A1 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BTG INTERNATIONAL LIMITED (GB) 1996-01-17 EP disclosed
US-5424194-A Chemiluminescence SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1995-06-13 US disclosed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO disclosed
EP-0505198-A1 A method of enhancing a luminescent reaction, luminometric assay and kits for use in the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1992-09-23 EP disclosed