Sugi Predict

Sugi Predict / Compounds / SCHEMBL6931607

SCHEMBL6931607

SCHEMBL6931607

CC(C)C1OC(=O)C(O)=C1O

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.57
▸ LMNA P02545 2/20 0.57
▸ L3MBTL1 Q9Y468 1/20 0.57
▸ HSPD1 P10809 1/20 0.44
▸ HSPE1 P61604 1/20 0.44
▸ TST Q16762 1/20 0.44
▸ RECQL P46063 1/20 0.44
▸ BLM P54132 1/20 0.44
▸ TDP1 Q9NUW8 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ MAPK1 P28482 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580853 0.98 MAPT (0.55) MAPTLMNAL3MBTL1HSPD1HSPE1
SCHEMBL21575597 0.84 MAPT (0.60) MAPTLMNAL3MBTL1HSPD1HSPE1
SCHEMBL12138177 0.84 MAPT (0.60) MAPTLMNAL3MBTL1HSPD1HSPE1
SCHEMBL14289768 0.84 MAPT (0.60) MAPTLMNAL3MBTL1HSPD1HSPE1
SCHEMBL14300895 0.81 MAPT (0.56) MAPTLMNAL3MBTL1HSPD1HSPE1
SCHEMBL25573446 0.80 MAPT (0.37) MAPTLMNAL3MBTL1HSPD1HSPE1
SCHEMBL14364471 0.80 MAPT (0.37) MAPTLMNAL3MBTL1HSPD1HSPE1
SCHEMBL19602911 0.79 MAPT (0.65) MAPTLMNAL3MBTL1HSPD1HSPE1
SCHEMBL21300814 0.79 MAPT (0.65) MAPTLMNAL3MBTL1HSPD1HSPE1
SCHEMBL13211430 0.79 MAPT (0.65) MAPTLMNAL3MBTL1HSPD1HSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112544619-B Bactericidal composition 沈阳中化农药化工研发有限公司 2022-04-12 — — CN claimed
US-20230165929-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS RENOVION, INC. 2023-06-01 — — US disclosed
CN-112544619-B Bactericidal composition 沈阳中化农药化工研发有限公司 2022-04-12 — — CN disclosed
CN-112544619-A Bactericidal composition 沈阳中化农药化工研发有限公司 2021-03-26 — — CN disclosed
US-20200397849-A1 STABLE ASCORBIC ACID COMPOSITIONS AND METHODS OF USING THE SAME RENOVION, INC. 2020-12-24 — — US disclosed
US-20190351005-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS RENOVION, INC. 2019-11-21 — — US disclosed
US-9850206-B2 S1P and/or ATX modulating agents BIOGEN MA INC. (US) 2017-12-26 — — US disclosed
US-8637507-B2 Bicyclic compounds as inhibitors of diacylglycerol acyltransferase MERCK SHARP & DOHME CORP. (US) 2014-01-28 — — US disclosed
US-20120022057-A1 BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYGLYCEROL ACYLTRANSFERASE SCHERING CORPORATION (US) 2012-01-26 — — US disclosed
US-20110319403-A1 BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE SCHERING CORPORATION (US) 2011-12-29 — — US disclosed
US-20110224137-A1 INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE MERCK SHARP & DOHME CORP. 2011-09-15 — — US disclosed
US-20110224136-A1 INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE MERCK SHARP & DOHME CORP 2011-09-15 — — US disclosed
EP-1246811-B1 METHODS FOR RESOLVING RACEMIC MIXTURES OF 5-SUBSTITUTED 4-HYDROXY-2-FURANONES OXIS ISLE OF MAN LTD (GB) 2003-12-03 — — EP disclosed
US-6613919-B2 Resolution with enantiomerically pure bases such as cinchonidine by forming a salt; also 3,4-dihydroxy-2(5H)-furanones OXIS ISLE OF MAN 2003-09-02 — — US disclosed
US-20030065196-A1 Method for resolving racemic mixtures of 5-substituted 4-hydroxy-2-furanones OXIS ISLE OF MAN 2003-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200397849-A1 STABLE ASCORBIC ACID COMPOSITIONS AND METHODS OF USING THE SAME GPX1, GPX4, GSTA1 MAPT 2550/4885LMNA 4739/4885L3MBTL1 3609/4885
US-20120022057-A1 BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYGLYCEROL ACYLTRANSFERASE DGAT2, DGAT1, LCAT MAPT 2445/4885LMNA 3371/4885L3MBTL1 1070/4885
US-20230165929-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS GPX1, GPX4, GSR MAPT 2926/4885LMNA 4498/4885L3MBTL1 2399/4885
US-20110224136-A1 INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE DGAT2, DGAT1, LCAT MAPT 2177/4885LMNA 3799/4885L3MBTL1 927/4885
US-20110319403-A1 BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE DGAT2, DGAT1, LCAT MAPT 2605/4885LMNA 3412/4885L3MBTL1 1423/4885
US-20190351005-A1 TREATMENT OF RESPIRATORY TRACT DISEASES AND INFECTIONS WITH ASCORBIC ACID COMPOSITIONS GPX1, GPX4, GSR MAPT 2926/4885LMNA 4498/4885L3MBTL1 2399/4885
US-20110224137-A1 INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE DGAT2, DGAT1, LCAT MAPT 2416/4885LMNA 3831/4885L3MBTL1 1258/4885
US-20030065196-A1 Method for resolving racemic mixtures of 5-substituted 4-hydroxy-2-furanones ADH1C, SRD5A2, SRD5A1 MAPT 4026/4885LMNA 633/4885L3MBTL1 4803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.