Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15267699 | 0.85 | KMT2A (0.60) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL6934236 | 0.82 | CA1 (0.58) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3911049 | 0.82 | CA12 (0.54) | ALDH1A1KMT2AMEN1POLBTP53 | |
| SCHEMBL7189672 | 0.82 | KMT2A (0.49) | SMN1; SMN2KMT2AMEN1MAPTPOLB | |
| SCHEMBL1561725 | 0.81 | MEN1 (0.56) | L3MBTL1KMT2AMEN1POLBKDM4E | |
| SCHEMBL7687241 | 0.81 | MAPT (0.62) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL6930363 | 0.81 | CA1 (0.56) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7753639 | 0.81 | NPC1 (0.59) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7895751 | 0.81 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6932064 | 0.80 | MAPT (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859000-B1 | Isoxazole amide and crotonamid derivatives and drug and diagnostic uses thereof | AVENTIS PHARMA GMBH (DE) | 2003-01-22 | — | — | EP | claimed |
| US-5977151-A | ANTITUMOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | claimed |
| WO-2023226241-A1 | PHENYLACETAMIDE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 湖南省农业生物技术研究所 | 2023-11-30 | — | — | WO | disclosed |
| WO-2020127508-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |
| US-6265588-B1 | USE AS PHARMACEUTICALS; AS AN ANTIGEN FOR PRODUCTION OF ANTIBODIES AND IN DIAGNOSIS AND PURIFICATION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| US-6121479-A | ANTIINFLAMMATORY AND ANTICARCINOGENIC AGENTS; AUTOIMMUNE DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |
| US-5977151-A | ANTITUMOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |