Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Ethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL27789134 | 1.00 | TSHR (0.62) | — | |
| Ethylene Glycol SCHEMBL6928678 | 0.94 | — | — | |
| Ethylene Glycol SCHEMBL564644 | 0.88 | — | — | |
| Ethylene Glycol SCHEMBL28377957 | 0.87 | TSHR (0.83) | — | |
| Ethylene Glycol SCHEMBL20487915 | 0.87 | — | — | |
| Ethylene Glycol SCHEMBL11329242 | 0.87 | TSHR (0.83) | — | |
| Ethylene Glycol SCHEMBL157946 | 0.87 | — | — | |
| Ethylene Glycol SCHEMBL1660501 | 0.87 | — | — | |
| Ethylene Glycol SCHEMBL7690439 | 0.87 | — | — | |
| Ethylene Glycol SCHEMBL8886271 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966888-A | Anhydrous magnesium chloride using ethylene glycol and ammonia | NALCO CHEMICAL COMPANY (US) | 1976-06-29 | — | — | US | claimed |
| CN-101462746-B | Method for preparing anhydrous magnesium chloride from bischofite | INST PROCESS ENG CAS | 2012-06-27 | — | — | CN | disclosed |
| CN-101734693-A | Method for preparing high-purity anhydrous magnesium chloride | KUN LI | 2010-06-16 | — | — | CN | disclosed |
| CN-101462746-A | Method for preparing anhydrous magnesium chloride from bischofite | INST PROCESS ENG CAS (CN) | 2009-06-24 | — | — | CN | disclosed |
| EP-0725761-B1 | ANHYDROUS MAGNESIUM CHLORIDE | COMMW SCIENT ANDINDUSTRIAL RES (AU) | 2003-12-10 | — | — | EP | disclosed |
| US-6143270-A | FORMING AN ALCOHOL MAGNESIUM CHLORIDE SOLUTION BY ADMIXING HYDRATED MAGNESIUM CHLORIDE WITH AN ALCOHOL WHICH IS MISCIBLE WITH WATER, DEHYDRATING, FORMING A PRECIPITATE COMPRISING MAGNESIUM CHLORIDE HEXAMMONIATE, WASHING, HEATING | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-11-07 | — | — | US | disclosed |
| EP-0725761-A4 | ANHYDROUS MAGNESIUM CHLORIDE | COMMW SCIENT IND RES ORG (AU) | 1998-01-07 | — | — | EP | disclosed |
| EP-0725761-A1 | ANHYDROUS MAGNESIUM CHLORIDE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1996-08-14 | — | — | EP | disclosed |
| WO-1995011859-A1 | ANHYDROUS MAGNESIUM CHLORIDE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-05-04 | — | — | WO | disclosed |
| US-3966888-A | Anhydrous magnesium chloride using ethylene glycol and ammonia | NALCO CHEMICAL COMPANY (US) | 1976-06-29 | — | — | US | disclosed |