SCHEMBL6933571

SCHEMBL6933571

C=Cc1ccc(S(=O)(=O)Nc2cc(OC)cc(OC)c2)cc1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.60
LMNA P02545 4/20 0.60
HTR6 P50406 1/20 0.59
CYP19A1 P11511 1/20 0.54
PKM P14618 3/20 0.53
MAPT P10636 1/20 0.53
FFAR4 Q5NUL3 2/20 0.50
GAA P10253 1/20 0.50
MAPK1 P28482 1/20 0.50
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
TP53 P04637 1/20 0.49
POLB P06746 1/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
TSHR P16473 1/20 0.48
HTT P42858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4822277 0.81 SMN1; SMN2 (0.67) SMN1; SMN2LMNAHTR6CYP19A1PKM
SCHEMBL5289106 0.80 SMN1; SMN2 (0.65) SMN1; SMN2LMNAHTR6CYP19A1PKM
SCHEMBL7823465 0.80 HTR6 (0.88) SMN1; SMN2LMNAHTR6CYP19A1PKM
SCHEMBL8752452 0.80 PGR (0.67) SMN1; SMN2LMNAHTR6CYP19A1PKM
SCHEMBL29048358 0.79 PTPN2 (0.57) PKMHDAC4HDAC1ALDH1A1HTT
SCHEMBL26536730 0.75 FFAR4 (0.60) SMN1; SMN2LMNAHTR6CYP19A1PKM
SCHEMBL15836440 0.75 CA1 (0.63) LMNAPKMMAPTFFAR4MAPK1
SCHEMBL11436261 0.75 CA12 (0.62) LMNAMAPTGAAMAPK1HDAC4
SCHEMBL14409393 0.74 KMT2A (0.67) PKMGAAHDAC4HDAC1ALDH1A1
SCHEMBL9300270 0.74 XDH (0.41) CYP19A1MAPTFFAR4GAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874282-B1 Negative working image recording material FUJI PHOTO FILM CO LTD (JP) 2003-12-10 EP disclosed
US-6083658-A ALKOXYMETHYL-SUBSTITUTED PHENOL CROSSLINKING AGENT, BINDER POLYMER, ACID GENERATOR, AND INFRARED RADIATION ABSORBER; LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 2000-07-04 US disclosed
EP-0874282-A1 Negative working image recording material FUJI PHOTO FILM CO., LTD. (JP) 1998-10-28 EP disclosed