Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6930687 | 0.79 | CA2 (0.36) | MAPTMEN1KMT2ACA2LMNA | |
| SCHEMBL6934334 | 0.78 | LMNA (0.40) | MAPTMEN1KMT2ACA2LMNA | |
| SCHEMBL6931540 | 0.75 | CA2 (0.33) | MAPTMEN1KMT2ACA2ALDH1A1 | |
| SCHEMBL6931469 | 0.74 | CA2 (0.35) | MAPTMEN1KMT2ACA2LMNA | |
| SCHEMBL6933858 | 0.71 | ELANE (0.42) | MEN1KMT2AALDH1A1TSHRELANE | |
| SCHEMBL8489871 | 0.69 | KMT2A (0.40) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6732622 | 0.66 | LMNA (0.39) | MEN1KMT2ACA2LMNAADORA3 | |
| SCHEMBL22214025 | 0.60 | CREBBP (0.39) | KMT2ALMNAALDH1A1POLBGAA | |
| SCHEMBL7358825 | 0.58 | MAPT (0.49) | MAPTMEN1KMT2ACA2LMNA | |
| SCHEMBL10246100 | 0.57 | LMNA (0.56) | MAPTMEN1KMT2ALMNAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |