Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489871 | 0.90 | KMT2A (0.40) | MEN1MAPTKMT2AGAALMNA | |
| SCHEMBL6930687 | 0.78 | CA2 (0.36) | CA2MEN1MAPTKMT2ALMNA | |
| SCHEMBL6930357 | 0.77 | ALOX12 (0.35) | ALOX12GAALMNAKDM4EGFER | |
| SCHEMBL6932809 | 0.74 | GAA (0.35) | MEN1MAPTKMT2AALOX12GAA | |
| SCHEMBL6932553 | 0.74 | GAA (0.35) | MAPTALOX12GAALMNAKDM4E | |
| SCHEMBL6932528 | 0.74 | GAA (0.38) | MAPTALOX12GAALMNAKDM4E | |
| SCHEMBL6931540 | 0.74 | CA2 (0.33) | CA2MEN1MAPTKMT2AGAA | |
| SCHEMBL6934334 | 0.74 | LMNA (0.40) | CA2MEN1MAPTKMT2ALMNA | |
| SCHEMBL6933858 | 0.73 | ELANE (0.42) | MEN1KMT2AALDH1A1DDB1CRBN | |
| SCHEMBL6932814 | 0.71 | ELANE (0.37) | MEN1MAPTKMT2AALOX12GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |