Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936100 | 0.83 | FAAH (0.44) | LMNANPSR1 | |
| SCHEMBL6933858 | 0.83 | ELANE (0.42) | NPSR1KMT2AMEN1ALDH1A1ELANE | |
| SCHEMBL6930687 | 0.79 | CA2 (0.36) | LMNAADORA3SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6933632 | 0.78 | MAPT (0.33) | LMNAADORA3KMT2AMEN1TDP1 | |
| SCHEMBL6931540 | 0.75 | CA2 (0.33) | NPSR1KMT2AMEN1CYP2C19ALDH1A1 | |
| SCHEMBL6931469 | 0.74 | CA2 (0.35) | LMNAKMT2AMEN1ALDH1A1CA2 | |
| SCHEMBL8489871 | 0.69 | KMT2A (0.40) | LMNASMN1; SMN2KMT2AMEN1CYP1A2 | |
| SCHEMBL6730883 | 0.66 | LMNA (0.50) | LMNAADORA3ATMSMN1; SMN2NPSR1 | |
| SCHEMBL6934455 | 0.66 | — | — | |
| SCHEMBL6934223 | 0.66 | ELANE (0.44) | SMN1; SMN2NPSR1KMT2AMEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903342-B1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-0903342-A1 | 4,4-Dihydroxypyrazolin-5-one compounds, procedures for their preparation and their use as cosmetics | L'OREAL (FR) | 1999-03-24 | — | — | EP | disclosed |