SCHEMBL6938457

SCHEMBL6938457

CC(=O)NNS(=O)(=O)c1cc2c[c]c(=O)[nH]c2cc1Cl

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCAT1 P54687 4/20 0.35
THRB P10828 1/20 0.34
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIA1 P42261 1/20 0.32
GRIA2 P42262 1/20 0.32
GRIA3 P42263 1/20 0.32
GRIA4 P48058 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
ATM Q13315 1/20 0.32
GLP1R P43220 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937174 0.83 KAT6A (0.46) BCAT1
SCHEMBL6940841 0.82 KMT2A (0.35) GRIN2DGRIN3BGRIA1GRIA2GRIA3
SCHEMBL6941830 0.82 KDM4E (0.30) GRIN2DGRIN3BGRIA1GRIA2GRIA3
SCHEMBL6935282 0.79 GSTO1 (0.38) ATM
SCHEMBL6934900 0.79 LMNA (0.33) THRB
SCHEMBL6937780 0.79 ALDH1A1 (0.41) GAAGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL7647451 0.77 BCAT1 (0.38) BCAT1THRBMGAMGAASI
SCHEMBL6934342 0.77 L3MBTL1 (0.40) GAAATM
SCHEMBL6934329 0.76 CA9 (0.46)
SCHEMBL6939756 0.76 GRIN2D (0.33) GRIN2DGRIN3BGRIA1GRIA2GRIA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1125942-B1 Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-04-09 EP disclosed
EP-1125942-A1 Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 2001-08-22 EP disclosed