Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438102 | 0.75 | MEN1 (0.55) | MEN1KMT2ATDP1POLBL3MBTL1 | |
| SCHEMBL1179747 | 0.75 | TDP1 (0.62) | MEN1KMT2ATDP1POLBKDM4E | |
| SCHEMBL29396391 | 0.75 | TDP1 (0.62) | MEN1KMT2ATDP1POLBKDM4E | |
| SCHEMBL7678635 | 0.75 | GLP1R (0.50) | MEN1KMT2A | |
| SCHEMBL6932438 | 0.75 | ALDH1A1 (0.41) | MEN1KMT2ATDP1POLBALDH1A1 | |
| SCHEMBL4158236 | 0.74 | MEN1 (0.47) | MEN1KMT2ATDP1POLBKDM4E | |
| SCHEMBL7103967 | 0.71 | TDP1 (0.51) | MEN1KMT2ATDP1POLBL3MBTL1 | |
| SCHEMBL1335613 | 0.71 | ALDH1A1 (0.69) | MEN1KMT2ATDP1POLBKDM4E | |
| SCHEMBL7483023 | 0.71 | MEN1 (0.53) | MEN1KMT2ATDP1POLBKDM4E | |
| SCHEMBL415237 | 0.71 | TDP1 (0.53) | MEN1KMT2ATDP1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | MERCK PATENT GMBH (DE) | 2003-11-06 | — | — | US | claimed |
| EP-1267819-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-01-02 | — | — | EP | claimed |
| WO-2001068047-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2001-09-20 | — | — | WO | claimed |
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | MERCK PATENT GMBH (DE) | 2003-11-06 | — | — | US | disclosed |
| EP-1267819-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068047-A2 | PREPARATION CONTAINING QUINOXALINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2001-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | CUTA, XPA, NQO2 | MEN1 942/4885KMT2A 1791/4885TDP1 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.