Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | TLR4 | O00206 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934815 | 1.00 | CYP1A2 (0.39) | CYP1A2CYP1A1CYP1B1LMNAGAA | |
| SCHEMBL6941385 | 0.81 | KDM4E (0.40) | KMT2APPARGCHEK1KDRFGFR1 | |
| SCHEMBL6941382 | 0.81 | KDM4E (0.40) | KMT2APPARGCHEK1KDRFGFR1 | |
| SCHEMBL6940624 | 0.76 | NCOA1 (0.42) | ALDH1A1 | |
| SCHEMBL4599983 | 0.75 | CYP3A4 (0.47) | CYP1A2LMNAKMT2ATTRALDH1A1 | |
| SCHEMBL242048 | 0.75 | LTA4H (0.50) | — | |
| SCHEMBL4599981 | 0.75 | CYP3A4 (0.47) | CYP1A2LMNAKMT2ATTRALDH1A1 | |
| SCHEMBL11209504 | 0.74 | MAOA (0.45) | CYP1A2LMNAGAAKMT2AALDH1A1 | |
| SCHEMBL6940160 | 0.73 | CYP3A4 (0.45) | CYP1A2KMT2APPARGALDH1A1HTT | |
| SCHEMBL7136291 | 0.72 | FURIN (0.53) | CYP1A2LMNAGAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0995739-B9 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORP (JP) | 2003-03-19 | — | — | EP | disclosed |
| EP-0995739-B1 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORP (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6248857-B1 | LOW MOISTURE RESISTANCE, HEAT RESISTANCE AND A LOW DIELECTRIC CONSTANT | NITTO DENKO CORPORATION (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0995739-A1 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORPORATION (JP) | 2000-04-26 | — | — | EP | disclosed |