Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5245987 | 0.87 | NNMT (0.41) | NNMTPOLBTDP1SIRT2SIRT1 | |
| SCHEMBL27517145 | 0.86 | NNMT (0.38) | NNMTPOLBTDP1SIRT2SIRT1 | |
| SCHEMBL5159486 | 0.84 | ALDH1A1 (0.38) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL5160842 | 0.81 | ALDH1A1 (0.44) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL19147472 | 0.80 | POLB (0.36) | NNMTPOLBTDP1MTNR1AMTNR1B | |
| SCHEMBL5160373 | 0.80 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL30294896 | 0.79 | PDE10A (0.40) | NNMTPOLBTDP1SIRT2SIRT1 | |
| SCHEMBL5707601 | 0.79 | LOXL2 (0.39) | NNMTPOLBTDP1SIRT2SIRT1 | |
| SCHEMBL15822496 | 0.79 | PDE10A (0.40) | NNMTPOLBTDP1SIRT2SIRT1 | |
| SCHEMBL5159318 | 0.79 | CD274 (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312606-A1 | 2,5-diaminopyridine oxidation bases and their use for dyeing of keratin fibres | L'OREAL (FR) | 2003-05-21 | — | — | EP | disclosed |