Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | VSIR | Q9H7M9 | 7/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160842 | 0.90 | ALDH1A1 (0.44) | ALDH1A1HSD17B10VSIRTSHRL3MBTL1 | |
| SCHEMBL5160373 | 0.89 | ALDH1A1 (0.46) | ALDH1A1HSD17B10VSIRTSHRL3MBTL1 | |
| SCHEMBL5159318 | 0.87 | CD274 (0.44) | VSIRPIK3CACD274PDCD1PDCD1LG2 | |
| SCHEMBL6935324 | 0.84 | NNMT (0.38) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL5245987 | 0.79 | NNMT (0.41) | ALDH1A1HSD17B10TSHRMTNR1AMTNR1B | |
| SCHEMBL27517145 | 0.78 | NNMT (0.38) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL29634740 | 0.74 | TNF (0.43) | ALDH1A1HSD17B10TSHRMTNR1AMTNR1B | |
| SCHEMBL94186 | 0.74 | TNF (0.43) | ALDH1A1HSD17B10TSHRMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7591939 | 0.73 | TNF (0.43) | ALDH1A1HSD17B10TSHRMTNR1AMTNR1B | |
| SCHEMBL15822496 | 0.72 | PDE10A (0.40) | ALDH1A1MTNR1AMTNR1BPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238211-B2 | 6-alkoxy-2,3-diaminopyridine couplers in which the amino radical in position 2 is a disubstituted amino radical, and use of these couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2007-07-03 | — | — | US | claimed |
| EP-1551360-B1 | 6-ALKOXY-2,3-DIAMINOPYRIDINE COUPLERS IN WHICH THE POSITION 2 AMINO RADICAL IS A DISUBSTITUTED AMINO RADICAL AND USE OF SAID COUPLERS FOR THE DYEING OF KERATINOUS FIBRES | OREAL (FR) | 2007-01-24 | — | — | EP | claimed |
| US-20060090270-A9 | Novel 6-alkoxy-2, 3-diaminopyridine couplers in which the amino radical in position 2 is a disubstituted amino radical, and use of these couplers for dyeing keratin fibres | VIDAL LAURENT | 2006-05-04 | — | — | US | claimed |
| US-7238211-B2 | 6-alkoxy-2,3-diaminopyridine couplers in which the amino radical in position 2 is a disubstituted amino radical, and use of these couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2007-07-03 | — | — | US | disclosed |
| US-20060090270-A9 | Novel 6-alkoxy-2, 3-diaminopyridine couplers in which the amino radical in position 2 is a disubstituted amino radical, and use of these couplers for dyeing keratin fibres | VIDAL LAURENT | 2006-05-04 | — | — | US | disclosed |
| US-20050086747-A1 | Novel 6-alkoxy-2, 3-diaminopyridine couplers in which the amino radical in position 2 is a disubstituted amino radical, and use of these couplers for dyeing keratin fibres | L'OREAL S.A. (FR) | 2005-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060090270-A9 | Novel 6-alkoxy-2, 3-diaminopyridine couplers in which the amino radical in position 2 is a disubstituted amino radical, and use of these couplers for dyeing keratin fibres | KRT18, QDPR, PYCR1 | ALDH1A1 292/4885HSD17B10 2251/4885VSIR 2042/4885 |
| US-20050086747-A1 | Novel 6-alkoxy-2, 3-diaminopyridine couplers in which the amino radical in position 2 is a disubstituted amino radical, and use of these couplers for dyeing keratin fibres | KRT18, QDPR, PYCR1 | ALDH1A1 292/4885HSD17B10 2251/4885VSIR 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.