SCHEMBL5707601

SCHEMBL5707601

COc1ccc(N)c(CN)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 2/20 0.39
LOX P28300 1/20 0.39
NNMT P40261 2/20 0.37
SIRT2 Q8IXJ6 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
TDP1 Q9NUW8 2/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 3/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PDE10A Q9Y233 3/20 0.32
TXNRD1 Q16881 2/20 0.32
PDE4B Q07343 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7564938 0.98 LOXL2 (0.38) LOXL2LOXNNMTSIRT2SIRT1
SCHEMBL15822496 0.84 PDE10A (0.40) NNMTSIRT2SIRT1TDP1POLB
SCHEMBL30294896 0.84 PDE10A (0.40) NNMTSIRT2SIRT1TDP1POLB
SCHEMBL5245987 0.84 NNMT (0.41) NNMTSIRT2SIRT1TDP1POLB
SCHEMBL13180961 0.81 NUDT1 (0.35) LOXL2LOXNNMTSIRT2SIRT1
SCHEMBL6935324 0.79 NNMT (0.38) NNMTSIRT2SIRT1TDP1POLB
SCHEMBL27517145 0.79 NNMT (0.38) NNMTSIRT2SIRT1TDP1POLB
SCHEMBL20143430 0.78 SIRT2 (0.33) NNMTSIRT2SIRT1TDP1POLB
SCHEMBL30660353 0.78 ALDH1A1 (0.38) NNMTSIRT2SIRT1TDP1POLB
SCHEMBL16364748 0.78 SIRT2 (0.33) NNMTSIRT2SIRT1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104853735-B For the autoxidizable reduction of the reagent of the oxidising dyeing and/or blast of keratin fiber 汉高股份有限及两合公司 2018-06-08 CN disclosed
CN-103622842-B Delivery of particles 宝洁公司 2017-10-27 CN disclosed
EP-1705227-A2 New dyestuffs and colorants with specific carbonyl compounds Henkel Kommanditgesellschaft auf Aktien (DE) 2006-09-27 EP disclosed
US-6828443-B1 Dyes and colorants HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-12-07 US disclosed
EP-1001734-B1 DYES HENKEL KGAA (DE) 2004-09-22 EP disclosed
CN-1166354-C Dyes �����ɷ� 2004-09-15 CN disclosed
EP-1189993-B1 NOVEL DYES AND COLORANTS HENKEL KGAA (DE) 2004-02-18 EP disclosed
EP-1189993-A1 NOVEL DYES AND COLORANTS Henkel Kommanditgesellschaft auf Aktien (DE) 2002-03-27 EP disclosed
WO-2001002492-A1 NOVEL DYES AND COLORANTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-01-11 WO disclosed
CN-1265578-A Dyes HENKEL KGAA (DE) 2000-09-06 CN disclosed
US-6090161-A AND FREE FROM OXIDATION DYE PRECURSORS OF THE PRIMARY INTERMEDIATE TYPE; ENABLE HAIR TO BE COLORED IN PARTICULAR IN BLACK TONES WITH NO TINGES OF RED; DYEING GREY HAIR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (KGAA) (DE) 2000-07-18 US disclosed
EP-1001734-A1 DYES Henkel Kommanditgesellschaft auf Aktien (DE) 2000-05-24 EP disclosed
WO-1999006016-A1 DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-02-11 WO disclosed