Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 5/20 | 0.45 |
| ▸ | CA9 | Q16790 | 5/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA4 | P22748 | 4/20 | 0.45 |
| ▸ | CA6 | P23280 | 4/20 | 0.45 |
| ▸ | CA5A | P35218 | 4/20 | 0.45 |
| ▸ | CA7 | P43166 | 4/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.45 |
| ▸ | CA3 | P07451 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1147613 | 0.81 | ALDH1A1 (0.56) | MAPTCA2CA1CA9CA12 | |
| SCHEMBL6940601 | 0.79 | ALDH1A1 (0.51) | HPGDGAAMAPTALDH1A1RAB9A | |
| SCHEMBL19617767 | 0.79 | POLB (0.55) | HPGDGAAMAPTCA2CA1 | |
| SCHEMBL2538350 | 0.78 | SIRT1 (0.50) | HPGDGAAMAPTCA2CA1 | |
| SCHEMBL1018224 | 0.77 | ALDH1A1 (0.51) | HPGDGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27950380 | 0.76 | NPSR1 (0.41) | HPGDGAAMAPTCA2CA1 | |
| SCHEMBL2543828 | 0.76 | POLB (0.55) | MAPTCA2CA1CA9CA12 | |
| SCHEMBL20495594 | 0.74 | MAOA (0.44) | HPGDGAAMAPTCA2CA1 | |
| SCHEMBL30548748 | 0.74 | MAOA (0.44) | HPGDGAAMAPTCA2CA1 | |
| SCHEMBL2543692 | 0.74 | HSD17B10 (0.51) | HPGDGAAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | claimed |