Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935543 | 0.79 | HPGD (0.48) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL5300150 | 0.75 | PPM1D (0.44) | ALDH1A1KMT2AHPGDRAB9AKDM4E | |
| SCHEMBL80348 | 0.73 | ALDH1A1 (0.43) | ALDH1A1KMT2AHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6942406 | 0.73 | HPGD (0.57) | ALDH1A1KMT2AHPGDMAPTTDP1 | |
| SCHEMBL5305669 | 0.73 | CTSD (0.42) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL77546 | 0.72 | KMT2A (0.40) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL6937373 | 0.71 | KMT2A (0.70) | ALDH1A1KMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL3954239 | 0.71 | HDAC3 (0.52) | ALDH1A1KMT2AHPGDMEN1RAB9A | |
| SCHEMBL6939482 | 0.71 | KMT2A (0.50) | ALDH1A1KMT2AHPGDGAATDP1 | |
| SCHEMBL77960 | 0.70 | ACHE (0.44) | ALDH1A1KMT2AHPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | claimed |