Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937072 | 0.83 | NPC1 (0.71) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL2386152 | 0.77 | ALDH1A1 (0.68) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL6938020 | 0.72 | NPC1 (0.53) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL21840821 | 0.71 | NPC1 (0.71) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL5888825 | 0.71 | WDR5 (0.53) | ALDH1A1MAPTPOLBKDM4EHPGD | |
| SCHEMBL6938522 | 0.71 | KEAP1 (0.66) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL1538693 | 0.70 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAL3MBTL1GLA | |
| SCHEMBL581124 | 0.67 | ALDH1A1 (1.00) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL28413604 | 0.67 | KMT2A (0.50) | ALDH1A1MAPTLMNAL3MBTL1GLA | |
| SCHEMBL27718058 | 0.67 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAL3MBTL1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |