Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 6/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928525 | 0.85 | AR (0.35) | PARP1AR | |
| SCHEMBL6935418 | 0.79 | CA2 (0.46) | ARCACNA1HGRIA1GRIA2GRIA3 | |
| SCHEMBL6934908 | 0.76 | TRPV4 (0.38) | GRIA1GRIA2GRIA3GRIA4CA12 | |
| SCHEMBL6932417 | 0.76 | CA12 (0.49) | PARP1ARGRIA1GRIA2GRIA3 | |
| SCHEMBL6937214 | 0.75 | ADORA3 (0.38) | — | |
| Phosphonic Acid SCHEMBL7070319 | 0.74 | CA1 (0.41) | CA12CA1CA2CA4CA6 | |
| SCHEMBL6937670 | 0.73 | KIF11 (0.35) | AR | |
| SCHEMBL7972493 | 0.72 | GRIA1 (0.53) | PARP1ARGRIA1GRIA2GRIA3 | |
| SCHEMBL6937263 | 0.70 | TSHR (0.42) | — | |
| SCHEMBL6935736 | 0.69 | CNR2 (0.37) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125941-B1 | Derivatives of 6-sulfamoyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125942-B1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-04-09 | — | — | EP | disclosed |
| EP-1125940-B1 | Derivatives of aryl or heteroaryl quinolinylphosphonic acids, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-01-15 | — | — | EP | disclosed |
| EP-1125942-A1 | Derivatives of 6-amino or 6-hydrazinosulfonyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |
| EP-1125940-A1 | Derivatives of aryl or heteroaryl quinolinylphosphonic acids, process for their preparation and pharmaceutical compositions containing them | Adir Et Cie (FR) | 2001-08-22 | — | — | EP | disclosed |
| EP-1125941-A1 | Derivatives of 6-sulfamoyl-3-quinolyl phosphonic acids, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-08-22 | — | — | EP | disclosed |