Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 13/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6486898 | 0.79 | METAP2 (0.60) | METAP2TDP1METAP1POLB | |
| SCHEMBL7359207 | 0.77 | METAP2 (0.72) | METAP2TDP1METAP1 | |
| SCHEMBL6935836 | 0.77 | METAP2 (0.46) | METAP2METAP1KMT2A | |
| SCHEMBL6939040 | 0.76 | METAP2 (0.46) | METAP2METAP1 | |
| Hydrochloric Acid SCHEMBL7357125 | 0.76 | METAP2 (0.71) | METAP2TDP1METAP1 | |
| SCHEMBL6938795 | 0.75 | METAP2 (0.64) | METAP2METAP1 | |
| SCHEMBL6564599 | 0.75 | METAP2 (0.64) | METAP2METAP1 | |
| SCHEMBL6938260 | 0.72 | PDK1 (0.45) | METAP2TDP1METAP1 | |
| SCHEMBL6561605 | 0.71 | METAP2 (0.64) | METAP2METAP1 | |
| SCHEMBL6937311 | 0.71 | METAP2 (0.51) | METAP2TDP1METAP1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | claimed |