Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072052 | 0.84 | MAPT (0.45) | MAPTHTTLMNATSHRMAPK1 | |
| SCHEMBL6938261 | 0.79 | LMNA (0.45) | LMNA | |
| SCHEMBL6940434 | 0.77 | ADA (0.56) | MAPTHTTLMNATSHRMAPK1 | |
| SCHEMBL6942807 | 0.75 | L3MBTL1 (0.44) | HTTTSHRL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL6941444 | 0.75 | KMO (0.44) | LMNAL3MBTL1SMN1; SMN2POLBKMT2A | |
| SCHEMBL6170042 | 0.73 | ADA (0.54) | MEN1 | |
| SCHEMBL6168401 | 0.72 | ADA (0.59) | MAPTLMNATDP1KMT2AMEN1 | |
| SCHEMBL6173074 | 0.72 | ADA (0.53) | — | |
| SCHEMBL6133390 | 0.71 | ADA (0.46) | MAPTLMNATDP1ALDH1A1KMT2A | |
| SCHEMBL6940404 | 0.71 | ADA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596738-B1 | Inhibiting activity to adenosine deaminase (hereinafter described as ADA) An adenosine deaminase inhibiting agent comprising a compound of the formula (I): | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-22 | — | — | US | disclosed |