Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | MDM4 | O15151 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937591 | 0.82 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1GAA | |
| SCHEMBL6942396 | 0.79 | TYR (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1GAA | |
| SCHEMBL6937909 | 0.78 | ALDH1A1 (0.39) | SLC6A2SLC6A4SLC6A3ALDH1A1GAA | |
| SCHEMBL6937295 | 0.72 | ALDH1A1 (0.37) | ALDH1A1GAAMAPTL3MBTL1POLB | |
| SCHEMBL7438728 | 0.72 | ALDH1A1 (0.46) | ALDH1A1GAAMAPTL3MBTL1POLB | |
| SCHEMBL21186437 | 0.72 | TSHR (0.46) | ALDH1A1POLB | |
| SCHEMBL6504953 | 0.71 | GABRA1 (0.47) | SLC6A2SLC6A4SLC6A3ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL4915526 | 0.71 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTL3MBTL1POLB | |
| SCHEMBL6934825 | 0.70 | ALOX15 (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1GAA | |
| SCHEMBL6934859 | 0.70 | ALDH1A1 (0.33) | SLC6A2SLC6A4SLC6A3ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |