Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938998 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MAPTGAANOS3NOS1 | |
| SCHEMBL6504953 | 0.80 | GABRA1 (0.47) | ALDH1A1MAPTGAANOS3NOS1 | |
| SCHEMBL844631 | 0.77 | ALDH1A1 (0.63) | ALDH1A1MAPTGAAPOLBGRIN2D | |
| SCHEMBL6940084 | 0.77 | TAS1R3 (0.42) | ALDH1A1MAPTGAANOS3NOS1 | |
| Bromide SCHEMBL20984235 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTGAAPOLBGRIN2D | |
| Hydrochloric Acid SCHEMBL1307931 | 0.75 | ALDH1A1 (0.61) | ALDH1A1MAPTGAAPOLBL3MBTL1 | |
| SCHEMBL6940133 | 0.74 | AOC3 (0.52) | NOS3NOS1NOS2L3MBTL1TAAR1 | |
| SCHEMBL7438728 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MAPTGAAPOLBL3MBTL1 | |
| SCHEMBL6937909 | 0.73 | ALDH1A1 (0.39) | ALDH1A1MAPTGAAPOLBL3MBTL1 | |
| SCHEMBL28224296 | 0.73 | AR (0.34) | ALDH1A1MAPTNOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |