Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504953 | 0.81 | GABRA1 (0.47) | AOC3TAAR1NOS3NOS1NOS2 | |
| SCHEMBL6938711 | 0.74 | ALDH1A1 (0.42) | TAAR1NOS3NOS1NOS2L3MBTL1 | |
| SCHEMBL6940084 | 0.74 | TAS1R3 (0.42) | AOC3NOS3NOS1NOS2L3MBTL1 | |
| SCHEMBL6547026 | 0.73 | SLC6A2 (0.49) | AOC3TAAR1MAOAMAOBNISCH | |
| SCHEMBL6547230 | 0.73 | SLC6A2 (0.49) | AOC3TAAR1MAOAMAOBNISCH | |
| SCHEMBL25215353 | 0.72 | SLC6A2 (0.47) | AOC3TAAR1TRPA1 | |
| SCHEMBL1952363 | 0.72 | SLC6A2 (0.47) | AOC3TAAR1TRPA1 | |
| SCHEMBL6545664 | 0.72 | TAAR1 (0.47) | AOC3TAAR1MAOAMAOBNISCH | |
| SCHEMBL11300405 | 0.72 | LMNA (0.49) | AOC3TAAR1TRPA1RIPK1 | |
| SCHEMBL9657114 | 0.72 | GABRA1 (0.61) | AOC3TAAR1MAOAMAOBNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |