SCHEMBL6938757

SCHEMBL6938757

Cn1c(Cl)c(-c2cc(OCC(F)(F)F)c(Cl)cc2F)c(Cl)c1C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
G6PD P11413 1/20 0.31
ALOX15 P16050 1/20 0.31
CASP1 P29466 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PYGL P06737 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6937162 0.86 PGK1 (0.35)
SCHEMBL6939632 0.86 ALOX5AP (0.30)
SCHEMBL6937330 0.85 PTGDR2 (0.39) KDM4EALDH1A1HSD17B10
SCHEMBL6940356 0.85 SCN9A (0.39)
SCHEMBL7693094 0.85 LMNA (0.33) MEN1KMT2AL3MBTL1
SCHEMBL6934937 0.85 LMNA (0.33) MEN1KMT2AL3MBTL1
SCHEMBL6940401 0.84 NR1I2 (0.31)
SCHEMBL6935030 0.83 PTGDR2 (0.34) MEN1KMT2A
SCHEMBL6937717 0.83 PPOX (0.35) MEN1MAPTKMT2A
SCHEMBL6937563 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1061072-B1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA SRL (IT) 2003-05-14 EP disclosed
US-6391827-B1 CONTROLLING WEEDS ISAGRO RICERCA S.R.L. (IT) 2002-05-21 US disclosed
EP-1061072-A1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA S.r.l. (IT) 2000-12-20 EP disclosed