SCHEMBL6940356

SCHEMBL6940356

Cn1c(Cl)c(-c2cc(OCC3CC3)c(Cl)cc2F)c(Cl)c1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 14/20 0.39
GRM2 Q14416 1/20 0.36
FFAR4 Q5NUL3 1/20 0.35
WDR5 P61964 1/20 0.34
KMO O15229 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6935070 0.86 SCN9A (0.31) SCN9A
SCHEMBL6938757 0.85 CNR2 (0.32)
SCHEMBL6939632 0.81 ALOX5AP (0.30)
SCHEMBL6937162 0.81 PGK1 (0.35)
SCHEMBL6935022 0.81 PPOX (0.41) SCN9AHTR2AHTR2CHTR2B
SCHEMBL7690087 0.81 GAA (0.38) SCN9AHTR2AHTR2CHTR2B
SCHEMBL6934937 0.80 LMNA (0.33)
SCHEMBL7693094 0.80 LMNA (0.33)
SCHEMBL6937330 0.80 PTGDR2 (0.39)
SCHEMBL6937563 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1061072-B1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA SRL (IT) 2003-05-14 EP disclosed
US-6391827-B1 CONTROLLING WEEDS ISAGRO RICERCA S.R.L. (IT) 2002-05-21 US disclosed
EP-1061072-A1 Pyrrolic compounds with a high herbicidal activity and their agronomic use ISAGRO RICERCA S.r.l. (IT) 2000-12-20 EP disclosed