Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | BCL2 | P10415 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940160 | 0.78 | CYP3A4 (0.45) | HTTSRD5A2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL22966330 | 0.77 | SRD5A2 (0.50) | POLBMAPTHTTSRD5A2ALDH1A1 | |
| SCHEMBL22966429 | 0.77 | SRD5A2 (0.50) | POLBMAPTHTTSRD5A2ALDH1A1 | |
| SCHEMBL22966339 | 0.76 | POLB (0.44) | POLBBCL2MCL1HTTSRD5A2 | |
| SCHEMBL6940624 | 0.76 | NCOA1 (0.42) | ALDH1A1HPGDHDAC8 | |
| SCHEMBL242048 | 0.75 | LTA4H (0.50) | SRD5A2 | |
| SCHEMBL6936469 | 0.74 | CYP3A4 (0.37) | POLBKDM4EALDH1A1 | |
| SCHEMBL17414463 | 0.74 | POLB (0.40) | POLBKDM4EAKR1C3PGRHDAC8 | |
| SCHEMBL145056 | 0.74 | ALDH1A1 (0.56) | POLBMAPTHTTSRD5A2ALDH1A1 | |
| SCHEMBL11437168 | 0.73 | PARP10 (0.55) | POLBMAPTSRD5A2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0995739-B9 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORP (JP) | 2003-03-19 | — | — | EP | disclosed |
| EP-0995739-B1 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORP (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6248857-B1 | LOW MOISTURE RESISTANCE, HEAT RESISTANCE AND A LOW DIELECTRIC CONSTANT | NITTO DENKO CORPORATION (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0995739-A1 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORPORATION (JP) | 2000-04-26 | — | — | EP | disclosed |