Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940160 | 0.88 | CYP3A4 (0.45) | CYP3A4TSHRKDM4EMEN1ALDH1A1 | |
| SCHEMBL6941382 | 0.78 | KDM4E (0.40) | CYP3A4KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL6941385 | 0.78 | KDM4E (0.40) | CYP3A4KDM4EMEN1ALDH1A1KMT2A | |
| Diphenylmethane SCHEMBL2583973 | 0.77 | CYP3A4 (0.63) | CYP3A4TSHRFFAR1 | |
| SCHEMBL6940624 | 0.76 | NCOA1 (0.42) | CYP3A4TSHRFFAR1FFAR4ALDH1A1 | |
| SCHEMBL4600058 | 0.75 | CYP3A4 (0.63) | CYP3A4TSHRFFAR1P2RY6ALDH1A1 | |
| SCHEMBL242048 | 0.75 | LTA4H (0.50) | CYP3A4TSHR | |
| SCHEMBL6938764 | 0.74 | POLB (0.50) | POLBKDM4EALDH1A1 | |
| SCHEMBL10441239 | 0.73 | CYP3A4 (0.55) | CYP3A4TSHRFFAR1FFAR4P2RY6 | |
| SCHEMBL7136291 | 0.72 | FURIN (0.53) | CYP3A4TSHRF2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0995739-B9 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORP (JP) | 2003-03-19 | — | — | EP | disclosed |
| EP-0995739-B1 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORP (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6248857-B1 | LOW MOISTURE RESISTANCE, HEAT RESISTANCE AND A LOW DIELECTRIC CONSTANT | NITTO DENKO CORPORATION (JP) | 2001-06-19 | — | — | US | disclosed |
| EP-0995739-A1 | Aromatic polycarbodiimide and polycarbodiimide sheet | NITTO DENKO CORPORATION (JP) | 2000-04-26 | — | — | EP | disclosed |