Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 12/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947321 | 0.82 | PPARG (0.43) | RENCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL6946632 | 0.82 | CYP1A2 (0.42) | RENCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL16511351 | 0.80 | ACHE (0.54) | RENCYP1A2CYP2C9CYP2C19KMT2A | |
| SCHEMBL21358212 | 0.78 | REN (0.58) | REN | |
| SCHEMBL6229093 | 0.77 | PDE4B (0.49) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL27930278 | 0.76 | STAT3 (0.45) | REN | |
| SCHEMBL8355373 | 0.74 | ALDH1A1 (0.54) | PDE4APDE4BPDE4CPDE4DCYP1A2 | |
| SCHEMBL8355366 | 0.74 | ALDH1A1 (0.54) | PDE4APDE4BPDE4CPDE4DCYP1A2 | |
| SCHEMBL8355369 | 0.74 | ALDH1A1 (0.54) | PDE4APDE4BPDE4CPDE4DCYP1A2 | |
| SCHEMBL2433356 | 0.74 | FDPS (0.46) | RENCYP1A2CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |