Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 10/20 | 0.40 |
| ▸ | FDPS | P14324 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947321 | 0.84 | PPARG (0.43) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL6938995 | 0.82 | REN (0.44) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL2433356 | 0.75 | FDPS (0.46) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL16511351 | 0.74 | ACHE (0.54) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL14778095 | 0.72 | REN (0.47) | REN | |
| SCHEMBL12524621 | 0.72 | KDM1A (0.45) | REN | |
| SCHEMBL18596510 | 0.72 | PPARG (0.54) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 | |
| SCHEMBL14114916 | 0.71 | ALOX15 (0.55) | REN | |
| SCHEMBL2738334 | 0.71 | ALOX15 (0.55) | REN | |
| SCHEMBL14476482 | 0.71 | REN (0.54) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |