SCHEMBL693909

SCHEMBL693909

Cc1cc(Cl)nc(Cl)c1[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.41
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 3/20 0.41
GRIN2D O15399 2/20 0.38
GRIN3B O60391 2/20 0.38
GRIN1 Q05586 2/20 0.38
GRIN2A Q12879 2/20 0.38
GRIN2B Q13224 2/20 0.38
GRIN2C Q14957 2/20 0.38
GRIN3A Q8TCU5 2/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
RAB9A P51151 1/20 0.35
MAPK1 P28482 1/20 0.35
DCTPP1 Q9H773 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29777009 1.00 TSHR (0.41) TSHRALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL28076936 0.87 ALDH1A1 (0.40) TSHRALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL27942931 0.85 MAPT (0.41) TSHRALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL29779688 0.85 ALDH1A1 (0.47) TSHRALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL1625178 0.85 ALDH1A1 (0.47) TSHRALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL5446122 0.81 MAPT (0.45) TSHRALDH1A1TDP1MEN1KMT2A
SCHEMBL26104768 0.81 ALDH1A1 (0.38) TSHRALDH1A1TDP1GRIN2DGRIN3B
SCHEMBL31569520 0.81 MAPT (0.45) TSHRALDH1A1TDP1MEN1KMT2A
SCHEMBL1693396 0.80 ALDH1A1 (0.54) TSHRALDH1A1GRIN2DGRIN3BGRIN1
SCHEMBL16244909 0.79 MAPT (0.49) TSHRALDH1A1TDP1GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114835639-B Preparation method of nevirapine intermediate 南京红太阳生物化学有限责任公司 2023-12-15 CN claimed
CN-114835639-A Preparation method of nevirapine intermediate 南京红太阳生物化学有限责任公司 2022-08-02 CN claimed
US-20260062427-A1 Bicyclic Ureas As Kinase Inhibitors INCYTE CORP (US) 2026-03-05 US disclosed
US-20260049093-A1 Bicyclic Ureas As Kinase Inhibitors INCYTE CORP (US) 2026-02-19 US disclosed
US-20260042781-A1 Bicyclic Ureas As Kinase Inhibitors INCYTE CORP (US) 2026-02-12 US disclosed
EP-4646411-A1 CDK2 INHIBITORS Blueprint Medicines Corporation (US) 2025-11-12 EP disclosed
US-20250214991-A1 BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS 2025-07-03 US disclosed
US-20250177363-A1 SUBSTITUTED IMIDAZOPYRIDINYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 BRISTOL-MYERS SQUIBB COMPANY (US) 2025-06-05 US disclosed
WO-2025101780-A1 PHARMACOLOGICAL CORRECTORS OF RHODOPSIN AND USES THEREOF OCTANT, INC. (US) 2025-05-15 WO disclosed
WO-2025056065-A1 CHEMOKINE RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION, AND USE 上海医药集团股份有限公司 2025-03-20 WO disclosed
EP-4499629-A1 BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2025-02-05 EP disclosed
US-20030236260-A1 Use of EP4 receptor ligands in the treatment of IL-6 involved diseases SHIMOJO MASATO 2003-12-25 US disclosed
WO-2003086371-A2 USE OF EP4 RECEPTOR LIGANDS IN THE TREATMENT OF IL-6 INVOLVED DISEASES PFIZER JAPAN INC. (JP) 2003-10-23 WO disclosed
EP-1326864-A2 ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS PFIZER PHARMACEUTICALS INC. (JP) 2003-07-16 EP disclosed
EP-1326606-A2 EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS PFIZER PHARMACEUTICALS INC. (JP) 2003-07-16 EP disclosed
US-20020107273-A1 Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents ASKAT INC. (JP) 2002-08-08 US disclosed
US-20020077329-A1 EP4 receptor inhibitors to treat rheumatoid arthritis PFIZER PHARMACEUTICALS INC. (JP) 2002-06-20 US disclosed
WO-2002032422-A2 EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS PFIZER PHARMACEUTICALS INC. (JP) 2002-04-25 WO disclosed
WO-2002032900-A2 ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS PFIZER PHARMACEUTICALS INC. (JP) 2002-04-25 WO disclosed
US-4068085-A YELLOW AND RED ON POLYESTERS AND ACRYLICS CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049093-A1 Bicyclic Ureas As Kinase Inhibitors OXSR1, JAK1, NCOR1 TSHR 157/4885ALDH1A1 1726/4885TDP1 3277/4885
US-20250177363-A1 SUBSTITUTED IMIDAZOPYRIDINYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 TLR9, TLR3, TLR1 TSHR 1671/4885ALDH1A1 2715/4885TDP1 280/4885
US-20020107273-A1 Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents PTGS1, PTGS2, OPRM1 TSHR 4596/4885ALDH1A1 588/4885TDP1 4486/4885
US-20030236260-A1 Use of EP4 receptor ligands in the treatment of IL-6 involved diseases PTGER4, PTGER1, IL6 TSHR 518/4885ALDH1A1 1858/4885TDP1 4244/4885
US-20260042781-A1 Bicyclic Ureas As Kinase Inhibitors NR0B1, NR2C2, ERBB2 TSHR 226/4885ALDH1A1 2073/4885TDP1 3704/4885
US-20250214991-A1 BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS IKZF1, IKZF2, IKZF3 TSHR 3900/4885ALDH1A1 3438/4885TDP1 2468/4885
US-20260062427-A1 Bicyclic Ureas As Kinase Inhibitors OXSR1, NCOR1, NR0B1 TSHR 106/4885ALDH1A1 2038/4885TDP1 3082/4885
US-20020077329-A1 EP4 receptor inhibitors to treat rheumatoid arthritis PTGER4, PTGER1, PTGER2 TSHR 351/4885ALDH1A1 1286/4885TDP1 3985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.