Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28814932 | 0.90 | CYP11B1 (0.41) | CYP11B2CYP11B1CYP19A1TYRO3NTRK2 | |
| Hydrochloric Acid SCHEMBL7177923 | 0.90 | TYRO3 (0.41) | CYP11B2CYP11B1CYP19A1TYRO3NTRK2 | |
| SCHEMBL19432718 | 0.88 | MMP3 (0.48) | CYP11B2CYP11B1CYP19A1TDP2MEN1 | |
| SCHEMBL7178824 | 0.86 | PTGS2 (0.42) | CYP11B2CYP11B1CYP19A1TYRO3NTRK2 | |
| SCHEMBL29672902 | 0.86 | PTGS2 (0.42) | CYP11B2CYP11B1CYP19A1TYRO3NTRK2 | |
| SCHEMBL30712626 | 0.84 | PTGS2 (0.41) | CYP11B2CYP11B1CYP19A1TYRO3NTRK2 | |
| SCHEMBL30712625 | 0.84 | PTGS2 (0.41) | CYP11B2CYP11B1CYP19A1TYRO3NTRK2 | |
| SCHEMBL8058170 | 0.81 | CYP11B2 (0.61) | CYP11B2CYP11B1CYP19A1IP6K1IP6K3 | |
| SCHEMBL6285180 | 0.81 | CYP11B2 (0.61) | CYP11B2CYP11B1CYP19A1IP6K1IP6K3 | |
| SCHEMBL28239652 | 0.80 | TDP2 (0.39) | CYP11B2CYP11B1CYP19A1TYRO3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104093749-A | Catalyst composition and process for preparing the same | SAUDI BASIC IND CORP SABIC | 2014-10-08 | — | — | CN | disclosed |
| CN-104080821-A | Catalyst composition and method for preparing the same | SAUDI BASIC IND CORP | 2014-10-01 | — | — | CN | disclosed |