SCHEMBL6940567

SCHEMBL6940567

Cc1cc2c(cc1C)C(O)C(Br)C2

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30082461 1.00 MEN1 (0.31) MEN1MAPTKMT2ANPSR1
SCHEMBL30666589 1.00 MEN1 (0.31) MEN1MAPTKMT2ANPSR1
SCHEMBL30666505 0.83 ACHE (0.36) MAPT
SCHEMBL6944525 0.79
SCHEMBL1852140 0.77 TRPM5 (0.40) KMT2A
SCHEMBL14785144 0.76 TRPM5 (0.36)
SCHEMBL30667077 0.76 HTR1A (0.36)
SCHEMBL22815741 0.76 HTR1A (0.36)
SCHEMBL30666675 0.76 ACHE (0.43) MAPT
SCHEMBL30082449 0.74 MEN1 (0.30) MEN1MAPTKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4110834-B1 ANSA-BIS(INDEN-2-YL) CATALYSTS FOR PRODUCING VINYLIDENE-TERMINATED POLYALPHAOLEFINS EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-04-03 EP disclosed
CN-113286831-B Substituted bis 2-indenyl metallocene compounds SABIC环球技术有限责任公司 2023-05-09 CN disclosed
US-11613593-B2 Ansa-bis(inden-2-yl) catalysts for producing vinylidene-terminated polyalphaolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-03-28 US disclosed
EP-3844196-B1 SUBSTITUTED BIS-2-INDENYL METALLOCENE COMPOUNDS SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-03-08 EP disclosed
CN-115485311-A Ansa-bis (inden-2-yl) catalysts for the production of vinylidene-terminated polyalphaolefins 埃克森美孚化学专利公司 2022-12-16 CN disclosed
US-11472895-B2 Substituted bis-2-indenyl metallocene compounds SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-10-18 US disclosed
CN-110494486-B Polypropylene resin composition, pellet, and molded article 出光兴产株式会社 2022-08-26 CN disclosed
CN-113286831-A Substituted bis 2-indenyl metallocene compounds SABIC环球技术有限责任公司 2021-08-20 CN disclosed
US-20210253749-A1 SUBSTITUTED BIS-2-INDENYL METALLOCENE COMPOUNDS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-08-19 US disclosed
EP-3844196-A1 SUBSTITUTED BIS-2-INDENYL METALLOCENE COMPOUNDS SABIC Global Technologies B.V. (NL) 2021-07-07 EP disclosed
US-11034826-B2 Polypropylene-based resin composition, pellet, and molded object IDEMITSU KOSAN CO., LTD. (JP) 2021-06-15 US disclosed
US-20200123360-A1 POLYPROPYLENE-BASED RESIN COMPOSITION, PELLET, AND MOLDED OBJECT IDEMITSU KOSAN CO., LTD. (JP) 2020-04-23 US disclosed
WO-2020043815-A1 SUBSTITUTED BIS-2-INDENYL METALLOCENE COMPOUNDS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-03-05 WO disclosed
EP-1157047-B1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORP NORTH AMERICA INC (US) 2003-04-23 EP disclosed
US-6479424-B1 FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. 2002-11-12 US disclosed
EP-1157047-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP Corporation North America Inc. (US) 2001-11-28 EP disclosed
WO-2000035975-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. (US) 2000-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613593-B2 Ansa-bis(inden-2-yl) catalysts for producing vinylidene-terminated polyalphaolefins RPSA, HNRNPA1, RAP1A MEN1 648/4885MAPT 2551/4885KMT2A 360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.